Software written by Dave Curtis
Below is a list of software I have written which is available for general
distribution. Many of the programs are redundant and are only provided for historical purposes
or because I have not bothered to remove them.
I use the MSVC compiler, and cross-platform development
of QDB, PEDRAW and DOLINK was achieved using the very wonderful
wxWindows
library which no longer seems to be available but which may have evolved into
wxWidgets.
The page for scoreassoc is here:
https://github.com/davenomiddlenamecurtis/scoreassoc
Page to get rs IDs for variants from their coordinates is here.
Page to get gene names from their symbols is here.
All the following stuff is no longer current. For software and scripts which I have been working on
more recently please visit my Github page at
https://github.com/davenomiddlenamecurtis?tab=repositories.
Packages from this site
are available using the links below.
All programs
are provided as DOS or
Windows executables and as source code in C and/or C++ to allow compilation on
other platforms. For programs under active development the version
numbers may change from time to time. If you have problems with any program, check back here to see that
you have the latest available version.
Dave Curtis software:
- mrvtest10.zip - MRVTEST - combined linkage and association test for rare variants
- clump24.zip - CLUMP - Monte Carlo method for assessing significance of case-control association studies with multi-allelic markers
- clumphap1_1.zip - CLUMPHAP - clustering method to test for haplotype associations
- etdt25.zip - ETDT - program to carry out TDT based on logistic regression for use with
multiallelic markers
- mflink34.zip - MFLINK - program to perform (nearly) model-free linkage analysis
- qmflink11.zip - QMFLINK - program for model-free linkage analysis of quantitative traits
- gcprog26.zip - support programs for GENECOUNTING to carry out association analyses with multiple markers
- combassoc13.zip - COMBASSOC - program to obtain overall significance of multiple analyses e.g. for gene-wise tests
- sibass14.zip - SIBASS - program to carry out association test using siblings as controls
- chhet10.zip - CHECKHET - program to detect genetic outliers in case-control samples
- wpdraw141.zip - PEDRAW - pedigree-drawing
program running under Windows or X
- pedraw25.zip - version 2.5 of PEDRAW, to compile with version 2.4 onwards of wxWindows library
- wqdb16i.zip - QDB - a general database program suitable for managing genetic data which runs under Windows or X
- qdb25.zip - version 2.5 of QDB, to compile with version 2.* of wxWindows library
- qdb26.zip - version 2.6 of QDB, to compile with version 2.4 onwards of wxWindows library
- sdt20.zip - SDT - program to carry out combined sibling control and TDT analysis
using Horvath and Laird's SDT method
- qlink16.zip - QUIKLINK - program to set up linkage analyses with a variety of programs
- table19.zip - TABLE - program to convert output from linkage analyses to
more readable form and to prepare input e.g. for graphing programs
- estat31.zip - EASISTAT - general statistics package
- powtest.zip - Excel spreadsheet to calculate power of ASP and TDT analyses
The following packages remain available mainly for historical reasons. They may be of academic interest, but
may not be of much practical value for modern data analysis.
- wdlink2l.zip - Windows/X version of DOLINK - a system for preparing data for linkage analysis
- fstmap12.zip - FASTMAP, produces quick approximation to multipoint lod score
- first11.zip - FIRSTORD, demonstration of method for preliminary ordering of loci based on two-point lod scores, available as DOS executable and C source
- erpa12f.zip - ERPA, program for carrying out nonparametric linkage analysis
To my homepage
David Curtis (email: d.curtis@ucl.ac.uk)